KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13L
All Species:
8.48
Human Site:
S1522
Identified Species:
15.56
UniProt:
Q71F56
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q71F56
NP_056150.1
2210
242602
S1522
A
T
L
Q
L
D
S
S
L
L
I
P
P
K
Y
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S1500
L
V
A
P
T
S
Q
S
L
I
T
P
P
Q
M
Rhesus Macaque
Macaca mulatta
XP_001112106
2210
242628
S1522
A
T
L
Q
L
D
S
S
L
L
I
P
P
K
Y
Dog
Lupus familis
XP_534693
2280
250152
L1592
T
L
Q
L
D
S
S
L
L
I
P
P
K
Y
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6JPI3
2207
241740
D1519
Y
L
A
T
L
Q
L
D
S
G
L
L
M
P
P
Rat
Rattus norvegicus
NP_001101807
1374
149708
Q710
P
P
A
E
A
Q
G
Q
A
T
P
G
N
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
A1482
Q
P
N
L
I
P
P
A
S
Q
P
V
P
T
P
Chicken
Gallus gallus
XP_415317
2195
241321
Y1508
S
L
L
L
P
P
K
Y
Q
T
P
A
P
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
Y1429
A
L
N
K
L
K
L
Y
A
H
V
C
R
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
N1936
L
Q
V
G
A
A
R
N
N
V
P
A
D
R
E
Honey Bee
Apis mellifera
XP_393643
1982
216109
R1318
Y
A
Q
V
C
N
H
R
L
A
P
Y
L
T
Q
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
I2115
Q
K
H
K
M
D
I
I
E
E
R
L
R
F
E
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
P463
F
C
R
A
Y
V
A
P
F
L
N
Q
E
Q
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
99.2
93.3
N.A.
92.4
57.7
N.A.
53.5
86.4
N.A.
50.2
N.A.
24.8
33.9
21.2
25.6
Protein Similarity:
100
69.3
99.6
94.7
N.A.
95.7
59.9
N.A.
69.7
92.5
N.A.
66.4
N.A.
41.5
50.5
38.5
35.1
P-Site Identity:
100
26.6
100
20
N.A.
6.6
0
N.A.
6.6
13.3
N.A.
13.3
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
40
100
26.6
N.A.
13.3
6.6
N.A.
20
20
N.A.
26.6
N.A.
26.6
13.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
24
8
16
8
8
8
16
8
0
16
0
16
0
% A
% Cys:
0
8
0
0
8
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
8
24
0
8
0
0
0
0
8
0
8
% D
% Glu:
0
0
0
8
0
0
0
0
8
8
0
0
8
0
16
% E
% Phe:
8
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
0
0
8
0
0
8
0
8
0
0
8
% G
% His:
0
0
8
0
0
0
8
0
0
8
0
0
0
8
0
% H
% Ile:
0
0
0
0
8
0
8
8
0
16
16
0
0
0
0
% I
% Lys:
0
8
0
16
0
8
8
0
0
0
0
0
8
16
0
% K
% Leu:
16
31
24
24
31
0
16
8
39
24
8
16
8
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
16
0
0
8
0
8
8
0
8
0
8
0
0
% N
% Pro:
8
16
0
8
8
16
8
8
0
0
47
31
39
8
24
% P
% Gln:
16
8
16
16
0
16
8
8
8
8
0
8
0
16
16
% Q
% Arg:
0
0
8
0
0
0
8
8
0
0
8
0
16
8
0
% R
% Ser:
8
0
0
0
0
16
24
24
16
0
0
0
0
0
8
% S
% Thr:
8
16
0
8
8
0
0
0
0
16
8
0
0
16
0
% T
% Val:
0
8
8
8
0
8
0
0
0
8
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
8
0
0
16
0
0
0
8
0
8
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _